San Francisco Burden of Disease & Injury Study:
Determinants of Health
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Contribution of Overweight/Obesity to SF Burden of Disease

The Population Attributable Fraction (PAF) for mortality is the proportional reduction in a specific cause of death that would have been expected if the population had no exposure to a specific determinant. It is calculated from the relative risk from exposure (RR) to the determinant and the prevalence of exposure to the determinant in the population (P), expressed as PAF = P(RR-1)/[P(RR-1) + 1]. Though it has limitations, PAF is an important measure for public health planning.

A reasonable first estimate of the PAF for all cause mortality associated with obesity (BMI of 30 or more) is as follows:

Assume the prevalence of obesity in SF is equal to that of US adults (Surgeon General's Call to Action--epi): 27%

Assume the RR for all cause mortality is between 1.5 and 2.0 (Surgeon General's Call to Action--health risks), or 1.75 for this estimate.

PAF = P(RR-1)/[P(RR-1) + 1] = 0.27(1.75 - 1)/[0.27(1.75 - 1) + 1 = 0.2025/1.2025 = 0.169 = 17%

This is a burden that may be greater than that of tobacco in San Francisco. (The relative risk associated with smoking is larger, but the prevalence is smaller.) Note, also, that there are great disparities in the prevalence of obesity among ethnic groups.

Separate estimates can be made for overweight (BMI 25-30) and for other health outcomes (eg, osteoarthitis of the knee, type 2 diabetes, ischemic heart disease, etc).

 

Overweight/Obesity

Overview

Contribution to overall disease burden in SF

Downstream (health consequences)

Upstream causes

What can be done?

Web resources

MEDLINE strategies

Updated April 25, 2005 • Please send feedback: brian.s.katcher@sfdph.org

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