San Francisco Burden of Disease & Injury Study:
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MEDLINE Search Strategies: High Blood Pressure

These recommendations are based on the PubMed interface to MEDLINE.

In mid-2006, there were more than a quarter of a million citations to articles about hypertension in MEDLINE, so some care must be taken in formulating focused search strategies. This is best accomplished by using takng advantage of MEDLINE's indexing by Medical Subject Headings (MeSH) and related subheadings.

If you begin your search by clicking on the link to the MeSH database on the left-hand side of the PubMed opening screen and type hypertension into the search box, you will find more than a dozen MeSH entries related to the word "hypertension." One of these is the MeSH "hypertension." Clicking on this link, you will see this page, where you can begin constructing a hypertenion search that is limited to specific subheadings. In addition, you can restrict your search to those papers in which hypertension (or hypertension resticted to specific subheadings) was the major topic of the article.

Here is an example of a search that is limited to hypertension/prevention and control as a major topic.

Additonal MeSH can be added to further narrow the search.

If we wanted to know something about preventing hypertension among African Americans, we would start with the steps above (hypertension as a major topic, limited to the subheading prevention and control). Then, instead of searching PubMed, we would enter another term into the MeSH database. Trying "blacks" we see that "African Continental Ancestry Group" is MeSH. Clicking on this link, we see that it is indeed the MeSH for "blacks," but looking at the relation of this term to other MeSH (bottom of the page), we see that "African Americans" is more specific. Clicking on the check box for African Americans and sending it to the search box, we have the search strategy "Hypertension/prevention and control"[MAJR] AND "African Americans"[MeSH]. Clicking on the "Search PubMed" button, we see these results -- fewer than one hundred articles on preventing hypertension among African Americans.

Here is an example of a search that is limited to hypertension/epidemiology as a major topic and further limited (AND) by the MeSH "United States." This search was recently used to determine the prevalence of hypertension in the U.S. Click on the "details" button to see how the search was formulated (in MEDLINE's language).

Because non-optimal blood pressures (those > 115 mm hg) are a significant contributor to morbidity and mortality, the MeSH blood pressure might be frutifully employed...

High Blood Pressure

Overview

Contribution to overall disease burden in SF

Downstream (Health Consequences)

Upstream Causes

What can be done?

Web resources

MEDLINE strategies

Updated August 7, 2006

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